Longitudinal infusion of a complex of insulin-like growth factor-I and IGF-binding protein-3 in five preterm infants: pharmacokinetics and short-term safety

BACKGROUND: In preterm infants, low levels of insulin-like growth factor-I (IGF-I) and IGF binding protein 3 (IGFBP-3) are associated with impaired brain growth and retinopathy of prematurity (ROP). Treatment with IGF-I/IGFBP-3 may be beneficial for brain development and may decrease the prevalence...

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Main Authors: Ley, David, Hansen-Pupp, Ingrid, Niklasson, Aimon, Domellöf, Magnus, Friberg, Lena E., Borg, Jan, Löfqvist, Chatarina, Hellgren, Gunnel, Smith, Lois E.H., Hård, Anna-Lena, Hellström, Ann
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028624/
https://ncbi.nlm.nih.gov/pubmed/23095978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.146
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