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Glucocorticoid receptor deletion from the dorsal raphé nucleus of mice reduces dysphoria-like behavior and impairs hypothalamic-pituitary-adrenocortical axis feedback inhibition

Glucocorticoids can cause depression and anxiety. Mechanisms for glucocorticoid effects on mood are largely undefined. The dorsal raphé nucleus (DRN) produces the majority of serotonin in the brain, and expresses glucocorticoid receptors (GR). Since we previously showed that antidepressants used to...

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Detalhes bibliográficos
Main Authors: Vincent, Melanie Y., Jacobson, Lauren
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028415/
https://ncbi.nlm.nih.gov/pubmed/24684372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12538
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