Avidity-Dependent Programming of Autoreactive T Cells in T1D

Fate determination for autoreactive T cells relies on a series of avidity-dependent interactions during T cell selection, represented by two general types of signals, one based on antigen expression and density during T cell development, and one based on genes that interpret the avidity of TCR inter...

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Hauptverfasser: Durinovic-Belló, Ivana, Gersuk, Vivian H., Ni, Chester, Wu, Rebecca, Thorpe, Jerill, Jospe, Nicholas, Sanda, Srinath, Greenbaum, Carla J., Nepom, Gerald T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028311/
https://ncbi.nlm.nih.gov/pubmed/24844227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098074
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