Luteolin Modulates 6-Hydroxydopamine-Induced Transcriptional Changes of Stress Response Pathways in PC12 Cells

The neurotoxin 6-hydroxydopamine (6-OHDA), which causes transcriptional changes associated with oxidative and proteotoxic stress, has been widely used to generate an experimental model of Parkinson’s disease. The food-derived compound luteolin has multi-target actions including antioxidant, anti-inf...

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Bibliographic Details
Main Authors: Hu, Ling-Wei, Yen, Jui-Hung, Shen, Yi-Ting, Wu, Kuan-Yi, Wu, Ming-Jiuan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028259/
https://ncbi.nlm.nih.gov/pubmed/24846311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097880
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