Allogeneic Splenocyte Transfer and Lipopolysaccharide Inhalations Induce Differential T Cell Expansion and Lung Injury: A Novel Model of Pulmonary Graft-versus-Host Disease

BACKGROUND: Pulmonary GVHD (pGVHD) is an important complication of hematopoietic cell transplant (HCT) and is thought to be a consequence of the HCT conditioning regimen, allogeneic donor cells, and posttransplant lung exposures. We have previously demonstrated that serial inhaled lipopolysaccharide...

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Main Authors: Martinu, Tereza, Kinnier, Christine V., Sun, Jesse, Kelly, Francine L., Nelson, Margaret E., Garantziotis, Stavros, Foster, W. Michael, Palmer, Scott M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028236/
https://ncbi.nlm.nih.gov/pubmed/24844383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097951
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