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Maternal KIR in combination with paternal HLA-C2 regulate human birth weight

Human birth weight is subject to stabilizing selection; babies born too small or too large are less likely to survive. Particular combinations of maternal/fetal immune system genes are associated with pregnancies where the babies are ≤5th birth weight centile. Specifically an inhibitory maternal KIR...

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Main Authors: Hiby, Susan E., Apps, Richard, Chazara, Olympe, Farrell, Lydia E., Magnus, Per, Trogstad, Lill, Gjessing, Håkon, Carrington, Mary, Moffett, Ashley
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028203/
https://ncbi.nlm.nih.gov/pubmed/24778445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400577
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