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Congenic Mapping and Allele-Specific Alteration Analysis of Stmm1 Locus Conferring Resistance to Early-Stage Chemically Induced Skin Papillomas

Genome-wide association studies have revealed that many low-penetrance cancer susceptibility loci are located throughout the genome; however, a very limited number of genes have been identified so far. Using a forward genetics approach to map such loci in a mouse skin cancer model, we previously ide...

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Auteurs principaux: Okumura, Kazuhiro, Saito, Megumi, Isogai, Eriko, Miura, Ikuo, Wakana, Shigeharu, Kominami, Ryo, Wakabayashi, Yuichi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028187/
https://ncbi.nlm.nih.gov/pubmed/24844776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097201
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