Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study

BACKGROUND: Understanding of the genetic basis of type 2 diabetes (T2D) has progressed rapidly, but the interactions between common genetic variants and lifestyle risk factors have not been systematically investigated in studies with adequate statistical power. Therefore, we aimed to quantify the co...

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Huvudupphovsmän: Langenberg, Claudia, Sharp, Stephen J., Franks, Paul W., Scott, Robert A., Deloukas, Panos, Forouhi, Nita G., Froguel, Philippe, Groop, Leif C., Hansen, Torben, Palla, Luigi, Pedersen, Oluf, Schulze, Matthias B., Tormo, Maria-Jose, Wheeler, Eleanor, Agnoli, Claudia, Arriola, Larraitz, Barricarte, Aurelio, Boeing, Heiner, Clarke, Geraldine M., Clavel-Chapelon, Françoise, Duell, Eric J., Fagherazzi, Guy, Kaaks, Rudolf, Kerrison, Nicola D., Key, Timothy J., Khaw, Kay Tee, Kröger, Janine, Lajous, Martin, Morris, Andrew P., Navarro, Carmen, Nilsson, Peter M., Overvad, Kim, Palli, Domenico, Panico, Salvatore, Quirós, J. Ramón, Rolandsson, Olov, Sacerdote, Carlotta, Sánchez, María-José, Slimani, Nadia, Spijkerman, Annemieke M. W., Tumino, Rosario, van der A, Daphne L., van der Schouw, Yvonne T., Barroso, Inês, McCarthy, Mark I., Riboli, Elio, Wareham, Nicholas J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028183/
https://ncbi.nlm.nih.gov/pubmed/24845081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001647
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