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Menin Directly Represses Expression of Gli1 Independent of the Canonical Hedgehog Signaling Pathway
Multiple Endocrine Neoplasia Type I (MEN1), a familial tumor syndrome results from mutations in the MEN1 gene, which encodes a tumor suppressor, menin. It has been previously shown that menin plays an important role in both repressing and activating gene expression. However, it is not well understoo...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028077/ https://ncbi.nlm.nih.gov/pubmed/23928057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0170 |
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