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Menin Directly Represses Expression of Gli1 Independent of the Canonical Hedgehog Signaling Pathway

Multiple Endocrine Neoplasia Type I (MEN1), a familial tumor syndrome results from mutations in the MEN1 gene, which encodes a tumor suppressor, menin. It has been previously shown that menin plays an important role in both repressing and activating gene expression. However, it is not well understoo...

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Hlavní autoři: Gurung, Buddha, Feng, Zijie, Hua, Xianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028077/
https://ncbi.nlm.nih.gov/pubmed/23928057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0170
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