Mutation and Gender Specific Risk in Type-2 Long QT Syndrome: Implications for Risk Stratification for Life-Threatening Cardiac Events in Patients with Long QT Syndrome

BACKGROUND: Men and women with type-2 long QT syndrome (LQT2) exhibit time-dependent differences in the risk for cardiac events. We hypothesized that data regarding the location of the disease-causing mutation in the KCNH2 channel may affect gender-specific risk in LQT2 OBJECTIVES: To risk stratify...

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Hoofdauteurs: Migdalovich, Dimitry, Moss, Arthur J., Lopes, Coeli M., Costa, Jason, Ouellet, Gregory, Barsheshet, Alon, McNitt, Scott, Polonsky, Slava, Robinson, Jennifer L., Zareba, Wojciech, Ackerman, Michael J., Benhorin, Jesaia, Kaufman, Elizabeth S., Platonov, Pyotr G., Shimizu, Wataru, Towbin, Jeffrey A., Vincent, G. Michael, Wilde, Arthur A.M., Goldenberg, Ilan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028036/
https://ncbi.nlm.nih.gov/pubmed/21440677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2011.03.049
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