Quantitative trait locus mapping of genetic modifiers of metabolic syndrome and atherosclerosis in LDL receptor deficient mice: identification of a locus for metabolic syndrome and increased atherosclerosis on chromosome 4

OBJECTIVE: To examine genetic factors responsible for metabolic syndrome and atherosclerosis in a setting of LDL receptor deficiency in a cross between C57BL/6J (B6) and PERA/Ei (PERA) inbred mouse strains. METHODS AND RESULTS: Comparison of metabolic phenotypes in B6 and PERA strains revealed the P...

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Bibliographic Details
Main Authors: Seidelmann, Sara Bretschger, De Luca, Carl, Leibel, Rudolph L., Breslow, Jan L., Tall, Alan R., Welch, Carrie L.
Format: Artigo
Language:Inglês
Published: 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027971/
https://ncbi.nlm.nih.gov/pubmed/15514201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000149146.32385.1b
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