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Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei

We have discovered a new mechanism of monoallelic gene expression that links antigenic variation, cell cycle, and development in the model parasite Trypanosoma brucei. African trypanosomes possess hundreds of variant surface glycoprotein (VSG) genes, but only one is expressed from a telomeric expres...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Batram, Christopher, Jones, Nicola G, Janzen, Christian J, Markert, Sebastian M, Engstler, Markus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027811/
https://ncbi.nlm.nih.gov/pubmed/24844706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02324
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