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New Hits as Antagonists of GPR103 Identified by HTS

[Image: see text] Preclinical data indicate that GPR103 receptor and its endogenous neuropeptides QRFP26 and QRFP43 are involved in appetite regulation. A high throughput screening (HTS) for small molecule GPR103 antagonists was performed with the clinical goal to target weight management by modulat...

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Detalhes bibliográficos
Main Authors: Nordqvist, Anneli, Kristensson, Lisbeth, Johansson, Kjell E., Isaksson da Silva, Krystle, Fex, Tomas, Tyrchan, Christian, Svensson Henriksson, Anette, Nilsson, Kristina
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027783/
https://ncbi.nlm.nih.gov/pubmed/24900874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400519h
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