Laddar...
FGFR1 Kinase Inhibitors: Close Regioisomers Adopt Divergent Binding Modes and Display Distinct Biophysical Signatures
[Image: see text] The binding of a ligand to its target protein is often accompanied by conformational changes of both the protein and the ligand. This is of particular interest, since structural rearrangements of the macromolecular target and the ligand influence the free energy change upon complex...
Sparad:
| Huvudupphovsmän: | , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Chemical
Society
2013
|
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027782/ https://ncbi.nlm.nih.gov/pubmed/24900792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4004205 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|