Novel Endoperoxide-Based Transmission-Blocking Antimalarials with Liver- and Blood-Schizontocidal Activities

[Image: see text] In a search for effective compounds against both the blood- and liver-stages of infection by malaria parasites with the ability to block the transmission of the disease to mosquito vectors, a series of hybrid compounds combining either a 1,2,4-trioxane or 1,2,4,5-tetraoxane and 8-a...

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Detalhes bibliográficos
Main Authors: Miranda, Daniela, Capela, Rita, Albuquerque, Inês S., Meireles, Patrícia, Paiva, Isa, Nogueira, Fátima, Amewu, Richard, Gut, Jiri, Rosenthal, Philip J., Oliveira, Rudi, Mota, Maria M., Moreira, Rui, Marti, Francesc, Prudêncio, Miguel, O’Neill, Paul M., Lopes, Francisca
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027774/
https://ncbi.nlm.nih.gov/pubmed/24900781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4002985
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