Digitoxin Analogues with Improved Anticytomegalovirus Activity

[Image: see text] Cardiac glycosides are potent inhibitors of cancer cell growth and possess antiviral activities at nanomolar concentrations. In this study we evaluated the anticytomegalovirus (CMV) activity of digitoxin and several of its analogues. We show that sugar type and sugar length attache...

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Detalhes bibliográficos
Main Authors: Cai, Hongyi, Wang, Hua-Yu L., Venkatadri, Rajkumar, Fu, De-Xue, Forman, Michael, Bajaj, Sumit O., Li, Hongyan, O’Doherty, George A., Arav-Boger, Ravit
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027591/
https://ncbi.nlm.nih.gov/pubmed/24900847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400529q
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