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Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors
[Image: see text] Matriptase belongs to trypsin-like serine proteases involved in matrix remodeling/degradation, growth regulation, survival, motility, and cell morphogenesis. Herein, we report a structure-based approach, which led to the discovery of sulfonamide and amide derivatives of pyridyl bis...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2013
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027570/ https://ncbi.nlm.nih.gov/pubmed/24900621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400213v |
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