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Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents
[Image: see text] Clopidogrel (CPG) is an antithrombotic prodrug that needs hepatic cytochrome P450 (CYP) enzymes for its bioactivation. The clinical effects of CPG have been associated with high intersubject variability and a certain level of resistance. Recently, comprehensive biotransformation st...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027567/ https://ncbi.nlm.nih.gov/pubmed/24900671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300460t |
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