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Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB(2) Receptors and Blockade of the Related GPR55

[Image: see text] The bark of Magnolia officinalis is used in Asian traditional medicine for the treatment of anxiety, sleeping disorders, and allergic diseases. We found that the extract and its main bioactive constituents, magnolol and honokiol, can activate cannabinoid (CB) receptors. In cAMP acc...

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Detalhes bibliográficos
Main Authors: Rempel, Viktor, Fuchs, Alexander, Hinz, Sonja, Karcz, Tadeusz, Lehr, Matthias, Koetter, Uwe, Müller, Christa E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027495/
https://ncbi.nlm.nih.gov/pubmed/24900561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300235q
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