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WalK, the Path towards New Antibacterials with Low Potential for Resistance Development

Resistance to antibiotics used in the treatment of bacterial infectious diseases is a global health problem. More than a decade ago, two-component systems such as WalKR were proposed as ideal targets for the development of new antibiotics. Biochemical screens for WalKR inhibitors using compound libr...

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Main Authors: Velikova, Nadya, Bem, Agnieszka E., van Baarlen, Peter, Wells, Jerry M., Marina, Alberto
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2013
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027477/
https://ncbi.nlm.nih.gov/pubmed/24900578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400320s
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