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Therapeutic rationale for low dose doxepin in insomnia patients

Histamine is an excitatory neurotransmitter in central nervous system. It plays an important role in the regulation of the sleep-wake cycle. Antidepressant with sleep-promoting effects, for example, doxepin, promotes sleep not through a sedative action but through resynchronisation of circadian cycl...

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Detalhes bibliográficos
Main Authors: Katwala, Jigar, Kumar, Ananda K, Sejpal, Jaykumar J, Terrence, Marcelle, Mishra, Manish
Formato: Artigo
Idioma:Inglês
Publicado em: Asian Pacific Tropical Medicine Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027305/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2222-1808(13)60080-8
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