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Scm3 deposits a (Cse4–H4)(2) tetramer onto DNA through a Cse4–H4 dimer intermediate

The assembly of centromeric nucleosomes is mediated by histone variant-specific chaperones. In budding yeast, the centromere-specific histone H3 variant is Cse4, and the histone chaperone Scm3 functions as a Cse4-specific nucleosome assembly factor. Here, we show that Scm3 exhibits specificity for C...

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Detalhes bibliográficos
Main Authors: Dechassa, Mekonnen Lemma, Wyns, Katharina, Luger, Karolin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027189/
https://ncbi.nlm.nih.gov/pubmed/24623811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku205
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