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Opioid-Induced Constipation: Pathophysiology, Clinical Consequences, and Management

Although opioids offer potent analgesia for severe acute and chronic noncancer pain, adverse gastrointestinal effects potentially undermine their clinical utility. In particular, between 40% and 95% of patients develop opioid-induced constipation (OIC). Therefore, there is a consensus that patients...

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Hlavní autoři: Kumar, Lalit, Barker, Chris, Emmanuel, Anton
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027019/
https://ncbi.nlm.nih.gov/pubmed/24883055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/141737
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