Predictive Simulation Approach for Designing Cancer Therapeutic Regimens with Novel Biological Mechanisms

Introduction Ursolic acid (UA) is a pentacyclic triterpene acid present in many plants, including apples, basil, cranberries, and rosemary. UA suppresses proliferation and induces apoptosis in a variety of tumor cells via inhibition of nuclear factor kappa-light-chain-enhancer of activated B cells (...

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Main Authors: Doudican, Nicole A., Mazumder, Amitabha, Kapoor, Shweta, Sultana, Zeba, Kumar, Ansu, Talawdekar, Anay, Basu, Kabya, Agrawal, Ashish, Aggarwal, Aditi, Shetty, Krithika, Singh, Neeraj K, Kumar, Chandan, Tyagi, Anuj, Singh, Neeraj Kumar, Darlybai, Janitha C, Abbasi, Taher, Vali, Shireen
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026994/
https://ncbi.nlm.nih.gov/pubmed/24847381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.7680
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