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Pathway-Driven Discovery of Rare Mutational Impact on Cancer

Identifying driver mutation is important in understanding disease mechanism and future application of custom tailored therapeutic decision. Functional analysis of mutational impact usually focuses on the gene expression level of the mutated gene itself. However, complex regulatory network may cause...

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Detalhes bibliográficos
Main Authors: Ahn, TaeJin, Park, Taesung
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026869/
https://ncbi.nlm.nih.gov/pubmed/24883302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/171892
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