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Eliminating Unwanted Far-Field Excitation in Objective-Type TIRF. Part I. Identifying Sources of Nonevanescent Excitation Light

Total internal reflection fluorescence microscopy (TIRFM) achieves subdiffraction axial sectioning by confining fluorophore excitation to a thin layer close to the cell/substrate boundary. However, it is often unknown how thin this light sheet actually is. Particularly in objective-type TIRFM, large...

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Detalhes bibliográficos
Main Authors: Brunstein, Maia, Teremetz, Maxime, Hérault, Karine, Tourain, Christophe, Oheim, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026778/
https://ncbi.nlm.nih.gov/pubmed/24606927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.049
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