New validated HPLC methodology for the determination of (−)-trans-paroxetine and its enantiomer in pharmaceutical formulations with use of ovomucoid chiral stationary phase

A new chromatographic method for the enantioseparation and the determination of (−)-trans-paroxetine and (+)-trans-paroxetine has been developed with the aid of amylose ovomucoid-based chiral stationary phase. The method is faster and five times more sensitive than procedures recommended previously:...

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Autors principals: Lisowska-Kuźmicz, Małgorzata, Kantor-Boruta, Małgorzata, Jończyk, Anna, Jarończyk, Małgorzata, Ocios-Bębenek, Agnieszka, Mazurek, Aleksander P., Chilmonczyk, Zdzisław, Jarosz, Maciej
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026622/
https://ncbi.nlm.nih.gov/pubmed/24408298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-013-7565-y
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