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Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system

Despite being one of the most promising amphiphilic block copolymers, use of Pluronic F68 in drug delivery is limited due to its high critical micelle concentration (CMC). In this study, we developed a novel F68 derivative, cholesterol-coupled F68 (F68-CHMC). This new derivative has a CMC of 10 μg/m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Song, Yanzhi, Tian, Qingjing, Huang, Zhenjun, Fan, Di, She, Zhennan, Liu, Xinrong, Cheng, Xiaobo, Yu, Bin, Deng, Yihui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026555/
https://ncbi.nlm.nih.gov/pubmed/24872693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S61220
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