Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system

Despite being one of the most promising amphiphilic block copolymers, use of Pluronic F68 in drug delivery is limited due to its high critical micelle concentration (CMC). In this study, we developed a novel F68 derivative, cholesterol-coupled F68 (F68-CHMC). This new derivative has a CMC of 10 μg/m...

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Hlavní autoři: Song, Yanzhi, Tian, Qingjing, Huang, Zhenjun, Fan, Di, She, Zhennan, Liu, Xinrong, Cheng, Xiaobo, Yu, Bin, Deng, Yihui
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026555/
https://ncbi.nlm.nih.gov/pubmed/24872693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S61220
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