Estrogen-Dependent Proteolytic Cleavage of Semaphorin 4D and Plexin-B1 Enhances Semaphorin 4D-Induced Apoptosis during Postnatal Vaginal Remodeling in Pubescent Mice

Around the fifth week after birth, the vaginal cavity in female mouse pups opens to the overlaying skin. This postnatal tissue remodeling of the genital tract occurs during puberty, and it largely depends upon hormonally induced apoptosis that mainly occurs in the epithelium at the lower part of the...

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Main Authors: Ito, Takuji, Bai, Tao, Tanaka, Tetsuji, Yoshida, Kenji, Ueyama, Takashi, Miyajima, Masayasu, Negishi, Takayuki, Kawasaki, Takahiko, Takamatsu, Hyota, Kikutani, Hitoshi, Kumanogoh, Atsushi, Yukawa, Kazunori
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026538/
https://ncbi.nlm.nih.gov/pubmed/24841081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097909
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