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TLR4 Activation Promotes Podocyte Injury and Interstitial Fibrosis in Diabetic Nephropathy

Toll like receptor (TLR) 4 has been reported to promote inflammation in diabetic nephropathy. However the role of TLR4 in the complicated pathophysiology of diabetic nephropathy is not understood. In this study, we report elevated expression of TLR4, its endogenous ligands and downstream cytokines,...

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Hlavní autoři: Ma, Jin, Chadban, Steven J., Zhao, Cathy Y., Chen, Xiaochen, Kwan, Tony, Panchapakesan, Usha, Pollock, Carol A., Wu, Huiling
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026484/
https://ncbi.nlm.nih.gov/pubmed/24842252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097985
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