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Streptococcus pneumoniae Interacts with pIgR Expressed by the Brain Microvascular Endothelium but Does Not Co-Localize with PAF Receptor

Streptococcus pneumoniae is thought to adhere to the blood-brain barrier (BBB) endothelium prior to causing meningitis. The platelet activating factor receptor (PAFR) has been implicated in this adhesion but there is a paucity of data demonstrating direct binding of the bacteria to PAFR. Additionall...

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Bibliographic Details
Main Authors: Iovino, Federico, Molema, Grietje, Bijlsma, Jetta J. E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026408/
https://ncbi.nlm.nih.gov/pubmed/24841255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097914
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