Synthesis, antimicrobial, and anti-inflammatory activity, of novel S-substituted and N-substituted 5-(1-adamantyl)-1,2,4-triazole-3-thiols

The reaction of 5-(1-adamantyl)-4-phenyl-1,2,4-triazoline-3-thione (compound 5) with formaldehyde and 1-substituted piperazines yielded the corresponding N-Mannich bases 6a–f. The reaction of 5-(1-adamantyl)-4-methyl-1,2,4-triazoline-3-thione 8 with various 2-aminoethyl chloride yielded separable mi...

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Detalhes bibliográficos
Main Authors: Al-Abdullah, Ebtehal S, Asiri, Hanadi H, Lahsasni, Siham, Habib, Elsayed E, Ibrahim, Tarek M, El-Emam, Ali A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026406/
https://ncbi.nlm.nih.gov/pubmed/24872681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S62465
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