Podocyte effacement closely links to suPAR levels at time of post-transplant focal segmental glomerulosclerosis occurrence and improves with therapy

BACKGROUND: Focal segmental glomerulosclerosis (FSGS) recurs after kidney transplantation in more than 30 % of cases and can lead to allograft loss. Serum soluble urokinase -type plasminogen activator receptor (suPAR) is implicated in the pathogenesis of native and recurrent FSGS. METHODS: We conduc...

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Huvudupphovsmän: Alachkar, Nada, Wei, Changli, Arend, Lois J., Jackson, Annette M., Racusen, Lorraine C, Fornoni, Alessia, Burke, George, Rabb, Hamid, Kakkad, Kavita, Reiser, Jochen, Estrella, Michelle M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026282/
https://ncbi.nlm.nih.gov/pubmed/23842190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31829eda4f
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