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Nimotuzumab in combination with radiotherapy in high grade glioma patients: A single institution experience
Nimotuzumab, a humanized antibody targeting epidermal growth factor receptor, has potent anti-proliferative, anti-angiogenic, and pro-apoptotic effects in vitro and in vivo. It also reduces the number of radio-resistant CD133(+) glioma stem cells. The antibody has been extensively evaluated in patie...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026072/ https://ncbi.nlm.nih.gov/pubmed/24521695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28021 |
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