Pediatric Brainstem Gangliogliomas Show BRAF(V600E) Mutation in a High Percentage of Cases

Brainstem gangliogliomas (GGs), often cannot be resected, have a much poorer prognosis than those located in more common supratentorial sites and may benefit from novel therapeutic approaches. Therapeutically targetable BRAF c.1799 T>A (p.V600E) (BRAF(V600E)) mutations are harbored in roughly 50%...

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Detaylı Bibliyografya
Asıl Yazarlar: Donson, Andrew M., Kleinschmidt‐DeMasters, Bette K., Aisner, Dara L., Bemis, Lynne T., Birks, Diane K., Levy, Jean M. Mulcahy, Smith, Amy A., Handler, Michael H., Foreman, Nicholas K., Rush, Sarah Z.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2013
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025990/
https://ncbi.nlm.nih.gov/pubmed/24238153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12103
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