Pediatric Brainstem Gangliogliomas Show BRAF(V600E) Mutation in a High Percentage of Cases

Brainstem gangliogliomas (GGs), often cannot be resected, have a much poorer prognosis than those located in more common supratentorial sites and may benefit from novel therapeutic approaches. Therapeutically targetable BRAF c.1799 T>A (p.V600E) (BRAF(V600E)) mutations are harbored in roughly 50%...

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Bibliografische gegevens
Hoofdauteurs: Donson, Andrew M., Kleinschmidt‐DeMasters, Bette K., Aisner, Dara L., Bemis, Lynne T., Birks, Diane K., Levy, Jean M. Mulcahy, Smith, Amy A., Handler, Michael H., Foreman, Nicholas K., Rush, Sarah Z.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2013
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025990/
https://ncbi.nlm.nih.gov/pubmed/24238153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12103
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