Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo

Antisense transcript, long non-coding RNA HOTAIR is a key player in gene silencing and breast cancer and is transcriptionally regulated by estradiol. Here, we have investigated if HOTAIR expression is misregulated by bisphenol-A (BPA) and diethylstilbestrol (DES). Our findings demonstrate BPA and DE...

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Hlavní autoři: Bhan, Arunoday, Hussain, Imran, Ansari, Khairul I., Bobzean, Samara A. M., Perrotti, Linda I., Mandal, Subhrangsu S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025971/
https://ncbi.nlm.nih.gov/pubmed/24533973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2014.02.002
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