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Integrated Analysis of Germline and Somatic Variants in Ovarian Cancer
We report the first large-scale exome-wide analysis of the combined germline-somatic landscape in ovarian cancer. Here we analyze germline and somatic alterations in 429 ovarian carcinoma cases and 557 controls. We identify 3,635 high confidence, rare truncation and 22,953 missense variants with pre...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025965/ https://ncbi.nlm.nih.gov/pubmed/24448499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4156 |
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