Sphingolipid Analogues Inhibit Development of Malaria Parasites

[Image: see text] Plasmodium-infected erythrocytes have been shown to employ sphingolipids from both endogenous metabolism as well as existing host pools. Therapeutic agents that limit these supplies have thus emerged as intriguing, mechanistically distinct putative targets for the treatment of mala...

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Main Authors: Meyer, Esmeralda V. S., Holt, Jason J., Girard, Kathryn R., Ballie, Mark T., Bushnev, Anatoliy S., Lapp, Stacey, Menaldino, David S., Arrendale, Richard F., Reddy, G. Prabhakar, Evers, Taylor J., Howard, Randy B., Culver, Deborah G., Liotta, Dennis C., Galinski, Mary R., Natchus, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2011
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025872/
https://ncbi.nlm.nih.gov/pubmed/24900369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2002136
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