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Gd Complexes of DO3A-(Biphenyl-2,2′-bisamides) Conjugates as MRI Blood-Pool Contrast Agents

[Image: see text] We report the synthesis of DO3A derivatives of 2,2′-diaminobiphenyl (1a,b) and their Gd complexes of the type [Gd(1)(H(2)O)]·xH(2)O (2a,b) for use as new MRI blood-pool contrast agents (BPCAs) that provide strong and prolonged vascular enhancement. Pharmacokinetic inertness of 2 co...

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Main Authors: Jung, Ki-Hye, Kim, Hee-Kyung, Park, Ji-Ae, Nam, Ki Soo, Lee, Gang Ho, Chang, Yongmin, Kim, Tae-Jeong
格式: Artigo
語言:Inglês
出版: American Chemical Society 2012
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025651/
https://ncbi.nlm.nih.gov/pubmed/24900422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300223b
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