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Gd Complexes of DO3A-(Biphenyl-2,2′-bisamides) Conjugates as MRI Blood-Pool Contrast Agents
[Image: see text] We report the synthesis of DO3A derivatives of 2,2′-diaminobiphenyl (1a,b) and their Gd complexes of the type [Gd(1)(H(2)O)]·xH(2)O (2a,b) for use as new MRI blood-pool contrast agents (BPCAs) that provide strong and prolonged vascular enhancement. Pharmacokinetic inertness of 2 co...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
American
Chemical Society
2012
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025651/ https://ncbi.nlm.nih.gov/pubmed/24900422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300223b |
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