Ultra-low-dose estriol and Lactobacillus acidophilus vaginal tablets (Gynoflor(®)) for vaginal atrophy in postmenopausal breast cancer patients on aromatase inhibitors: pharmacokinetic, safety, and efficacy phase I clinical study

Phase I pharmacokinetic (PK) study assessed circulating estrogens in breast cancer (BC) patients on a non-steroidal aromatase inhibitor (NSAI) with vaginal atrophy using vaginal ultra-low-dose 0.03 mg estriol (E3) and Lactobacillus combination vaginal tablets (Gynoflor(®)). 16 women on NSAI with sev...

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Hlavní autoři: Donders, Gilbert, Neven, Patrick, Moegele, Maximilian, Lintermans, Anneleen, Bellen, Gert, Prasauskas, Valdas, Grob, Philipp, Ortmann, Olaf, Buchholz, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
Clinical Trial
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025172/
https://ncbi.nlm.nih.gov/pubmed/24718774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-2930-x
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