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Phenotypic switching in gene regulatory networks

Noise in gene expression can lead to reversible phenotypic switching. Several experimental studies have shown that the abundance distributions of proteins in a population of isogenic cells may display multiple distinct maxima. Each of these maxima may be associated with a subpopulation of a particul...

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Bibliographische Detailangaben
Hauptverfasser: Thomas, Philipp, Popović, Nikola, Grima, Ramon
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024914/
https://ncbi.nlm.nih.gov/pubmed/24782538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400049111
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