The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin

Malaria is caused by a protozoan parasite that replicates within an intraerythrocytic parasitophorous vacuole. Release (egress) of malaria merozoites from the host erythrocyte is a highly regulated and calcium-dependent event that is critical for disease progression. Minutes before egress, an essent...

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Bibliographic Details
Main Authors: Withers-Martinez, Chrislaine, Strath, Malcolm, Hackett, Fiona, Haire, Lesley F., Howell, Steven A., Walker, Philip A., Evangelos, Christodoulou, Dodson, Guy G., Blackman, Michael J.
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024747/
https://ncbi.nlm.nih.gov/pubmed/24785947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4726
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