Elastase and Cathepsin G from Primed Leukocytes Cleave Vascular Endothelial Cadherin in Hemodialysis Patients

Aims. To test the hypothesis that primed PMNLs in blood of chronic kidney disease patients release the active form of elastase and cathepsin G causing degradation of vital proteins and promote tissue damage. Methods. RT-PCR, immunocytochemical staining, immunoblotting, and FACS analyses were used to...

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Autors principals: Cohen-Mazor, Meital, Mazor, Rafi, Kristal, Batya, Sela, Shifra
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024418/
https://ncbi.nlm.nih.gov/pubmed/24877096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/459640
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