Assessment of Mutational Load in Biopsy Tissue Provides Additional Information About Genomic Instability to Histological Classifications of Barrett's Esophagus

PURPOSE: Progression of Barrett's esophagus (BE) to esophageal adenocarcinoma (EAC) is associated with accumulated genomic instability. Current risk stratification of BE for EAC relies on histological classification and grade of dysplasia. However, histology alone cannot assess the risk of pati...

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Détails bibliographiques
Auteurs principaux: Khara, Harshit S., Jackson, Sara A., Nair, Saraswathi, Deftereos, Georgios, Patel, Shweta, Silverman, Jan F., Ellsworth, Eric, Sumner, Cameron, Corcoran, Brendan, Smith, Dennis M., Finkelstein, Sydney, Gross, Seth A.
Format: Artigo
Langue:Inglês
Publié: Springer US 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024388/
https://ncbi.nlm.nih.gov/pubmed/24402860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12029-013-9570-y
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