p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice

BACKGROUND: There is a need for agents that suppress inflammation and progression of chronic obstructive pulmonary disease. p38 mitogen-activated protein kinase (p38 MAPK) has been associated with this disorder, and several inhibitors of this cascade are in clinical trials for its treatment, but the...

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Autori principali: Marumo, Satoshi, Hoshino, Yuma, Kiyokawa, Hirofumi, Tanabe, Naoya, Sato, Atsuyasu, Ogawa, Emiko, Muro, Shigeo, Hirai, Toyohiro, Mishima, Michiaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024315/
https://ncbi.nlm.nih.gov/pubmed/24885161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-14-79
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