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COOH-Terminal Collagen Q (COLQ) Mutants Causing Human Deficiency of Endplate Acetylcholinesterase Impair the Interaction of ColQ with Proteins of the Basal Lamina

Collagen Q (ColQ) is a key multidomain functional protein of the neuromuscular junction (NMJ), crucial for anchoring acetylcholinesterase (AChE) to the basal lamina (BL) and accumulating AChE at the NMJ. The attachment of AChE to the BL is primarily accomplished by the binding of the ColQ collagen d...

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Bibliografske podrobnosti
Main Authors: Arredondo, Juan, Lara, Marian, Ng, Fiona, Gochez, Danielle A., Lee, Diana C., Logia, Stephanie P., Nguyen, Joanna, Maselli, Ricardo A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024244/
https://ncbi.nlm.nih.gov/pubmed/24281389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1391-3
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