The use of vismodegib to shrink keratocystic odontogenic tumors in basal cell nevus syndrome patients

IMPORTANCE: Keratocystic odontogenic tumors of the jaw (KCOTs) affect more than 65% of patients with basal cell nevus syndrome (BCNS). Surgery frequently causes facial disfigurement and is not always curative. Most BCNS-related and some sporadic KCOTs have malignant activation of the Hedgehog (HH) s...

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Autori principali: Ally, Mina S., Tang, Jean Y., Joseph, Timmy, Thompson, Bobbye, Lindgren, Joselyn, Raphael, Maria Acosta, Ulerio, Grace, Chanana, Anita M., Mackay-Wiggan, Julian M., Bickers, David R., Epstein, Ervin H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024084/
https://ncbi.nlm.nih.gov/pubmed/24623282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2013.7444
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