Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8(+) T Cells

In human tuberculosis (TB), CD8(+) T cells contribute to host defense by the release of Th1 cytokines and the direct killing of Mycobacterium tuberculosis (Mtb)-infected macrophages via granule exocytosis pathway or the engagement of receptors on target cells. Previously we demonstrated that strain...

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Hauptverfasser: Geffner, Laura, Basile, Juan Ignacio, Yokobori, Noemí, Kviatcovsky, Denise, Sabio y García, Carmen, Ritacco, Viviana, López, Beatriz, Sasiain, María del Carmen, de la Barrera, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024032/
https://ncbi.nlm.nih.gov/pubmed/24836916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097837
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